Peter Cotton, MD
Dr. Cotton is Professor of Medicine in the Division of Gastroenterology and Hepatology, at the Medical University of South Carolina (MUSC) in Charleston, where he founded the Digestive Disease Center in 1994.
He was born in 1939 in England, where his father was a rural family physician. He graduated in 1963 from Cambridge University and St. Thomas Hospital Medical School (London). He developed the Endoscopy Laboratory at St. Thomas’ Hospital while still officially in training, and brought ERCP back from Japan in 1971. In 1973 he was appointed to the faculty of the Middlesex Hospital and Medical School (London) as Director of Gastroenterology, where he developed a new department integrating medical and surgical gastroenterology, with an emphasis on endoscopic therapy and teaching. His group pioneered many diagnostic and therapeutic endoscopy procedures, particularly ERCP (sphincterotomy and stenting) and was very active in teaching. He attracted postgraduates from many countries, held numerous teaching courses, and pioneered live CCTV workshops.
Dr. Cotton left England in 1986 to become Professor of Medicine and Chief of Endoscopy at Duke University, Durham, North Carolina. He developed a state of the art endoscopy center. He maintained his interests in teaching (mainly through live video courses), new techniques, and careful outcome evaluation. He moved to Charleston, South Carolina in 1994.
The mission of the Digestive Disease Center is to provide multidisciplinary patient-friendly, cost-effective patient care, and to pursue the research and teaching necessary to enhance it. The diverse and international team develops new techniques, and is dedicated to their scientific evaluation. This work includes emphasis on consensus definitions of patients, lesions, intervention and outcomes, and their incorporation in electronic databases.
Dr. Cotton has been active in many national and international organizations, and has given invited lectures and demonstrations in more than 50 countries. He helped form the British Society for Digestive Endoscopy, and served the British Society of Gastroenterology as its vice president and treasurer. He was secretary of the European Society for Gastrointestinal Endoscopy, and president of the Pancreatic Society of Great Britain. He was elected Fellow of the Royal College of Physicians (London) in 1978, Fellow of the Royal College of Physicians and Surgeons (Glasgow) in 1997, and Fellow of the Royal College of Surgeons (London) in 2002. He is an honorary member of the British Society of Gastroenterology, the Hong Kong Society for Digestive Endoscopy, and the South African Gastroenterology Society. Dr Cotton was awarded the Rudolph Schindler award of the American Society for Gastrointestinal Endoscopy in 2004.
His bibliography includes over 900 medical publications, including more than 300 original contributions in peer reviewed journals, and 10 books. “Practical Gastrointestinal Endoscopy” (co-authored by Christopher Williams) is the standard endoscopy teaching text, currently in its 6th Edition, and has been translated into 8 languages. He has been on the editorial boards of 12 gastroenterology journals, and was the first international editor of Gastrointestinal Endoscopy. He recently published his “endoscopic memoirs” called “The tunnel at the end of the light”, available at www.peterbcotton.com, and a series of children’s books starting with “When Fred the Snake got Squished and Mended”, available at Amazon.com, and www.petercottontales.com.
Paul Covington, MD
Dr. Covington currently (2015 to present) consults with the pharmaceutical industry. His expertise includes: over 25 years of strategic drug development (especially US), drug safety, regulatory strategy, and protocol design. Dr. Covington is Board Certified in Internal Medicine and was in private practice from 1985-1990. Following that he was an investigator for Future Healthcare Research Centers actively recruiting volunteers for both patient studies as well as normal healthy volunteer studies. Subsequently he spent 19 years with PPD, a contract research organization, where he advanced to Executive VP and was responsible for global safety, global regulatory affairs, GMP laboratories, bioanalytical laboratories, central laboratories, Phase I healthy volunteer unit, post approval medical information and post approval clinical studies while still playing a critical role in all pre-approval studies. Dr. Covington has been both directly and indirectly involved in literally hundreds of clinical trials over a variety of indications and has attended and/or presided over (from the sponsor standpoint) 15 meetings with FDA. Dr. Covington decided to retire in 2008 but was enticed to rejoin PPD in late 2009 to spin out Furiex Pharmaceuticals (FP) where he was responsible for all clinical development and IT. He remained with FP throughout its existence as well as following its acquisition by Actavis (now Allergan). At spinout from PPD, FP had an IPO stock price of approximately $10/share (June 2010) and was subsequently sold in July 2014 at approximately $100/share. Dr. Covington has over 20 publications in peer reviewed journals. His hobbies include Christian Church History and long-distance cycling.
Anthony Lembo, MD
Anthony Lembo, MD, is Director of the GI Motility and Functional Bowel Disorders Program at Beth Israel Deaconess Medical Center and Associate Professor of Medicine at Harvard Medical School in Boston, Mass. Dr. Lembo earned his medical degree from Tufts University School of Medicine in Boston and completed his residency in medicine, as well as fellowships in gastroenterology and gastrointestinal motility and irritable bowel syndrome (IBS), at the University of California, Los Angeles, (UCLA) Medical Center. Dr. Lembo’s research interests focus on the burden of and treatment options for irritable bowel syndrome (IBS) and chronic constipation, and he also studies the placebo response. He has published widely on these topics, in leading peer-reviewed journals such as Gastroenterology, Neurogastroenterology and Motility, Alimentary Pharmacology & Therapeutics, Clinical and Translational Gastroenterology as well as Digestive Diseases and Sciences. He also served as an editor or on the review board for several industry renowned journals, including the New England Journal of Medicine, American Journal of Gastroenterology, Gastroenterology & Hepatology, Journal of Gastroenterology and Hepatology Research and most recently, American Journal of Case Reports. Dr. Lembo is also an active member of many professional societies including the American Gastroenterological Association, the American Neurogastroenterology and Motility Society, and the American College of Gastroenterology. He has been appointed numerous national and international leadership positions throughout his tenure.
Gail McIntyre, PhD, DABT
Dr. McIntyre has more than 25 years of experience in the drug discovery and development industry. She has authored more than 30 regulatory submissions and is a board certified toxicologist with extensive experience in moving compounds through lead optimization and clinical development onto the market. Her experience covers multiple therapeutic areas including oncology (recently immune-oncology), infectious diseases, central nervous system, gastrointestinal, and metabolic/endocrine as well as various therapies including small drugs, treatment vaccines, immunomodulators, antibodies, immunoconjugates and peptide mimetics. Dr. McIntyre is also board certified in Clinical Pathology (hematology and clinical chemistry) by the American Society of Clinical Pathology. She held the position of Senior Vice President of Research at Furiex Pharmaceuticals, Inc. from April 1, 2010 until December 2015 and she served as head of Pharmaceutical Product Development LLC’s compound partnering business for 12 years prior to that. She started her own consulting business in 2015, Intellidev Consulting, LLC.
Dr. McIntyre received her B.A. in Biology from Merrimack College. She earned M.S. and Ph.D. degrees in Biochemistry and Biophysics from the University of North Carolina at Chapel Hill.
Pankaj Jay Pasricha, MBBS, MD
Recruited from Stanford University, where he was chief of gastroenterology for five years, Dr. Pasricha is leading the establishment of the Johns Hopkins Center for Neurogastroenterology. Patients with motility disorders as well as diseases ranging from Parkinsons to Autism, and diabetes to obesity, stand to benefit from his research, which focuses on clinical disorders associated with gastroenterological motility, the biology of the enteric nervous system and visceral pain, neural stem cells and technology development associated with endoscopic research and advancements.
Over the course of his career, Dr. Pasricha has been credited with more than 30 patents for novel gastrointestinal diagnosis and treatment methods. His extensive publications on the enteric nervous system and gut-brain axis have garnered global attention.
Dr. Pasricha practices at The Johns Hopkins Hospital and Johns Hopkins Bayview Medical Center. He is also Professor of Innovation Management at the Johns Hopkins Carey School of Business.
Frank Steinberg, DO
Dr. Steinberg is a board certified pediatrician with over 30 years of pharmaceutical industry experience. He has a BS in Pharmacy from Temple University and a DO degree from the Philadelphia College of Osteopathic Medicine. During his industry tenure as Vice President of Medical Affairs at Abbott Laboartories, President of Lorex Pharmaceuticals (A Searle/Sanofi JV), VP of Worldwide Licensing for Searle and CMO at Transcept Pharmaceuticals, he was responsible for development of several products including seven (7) NDA approvals. He has clinical development experience in several therapeutic areas, including cardiovascular, infectious disease, neurology, psychiatry, oncology and pediatric drug development. He is a fellow of the American Academy of Pediatrics, a member of the Academy Clinical Pharmacology subsection and was previously on the Board of Directors of the National Sleep Foundation. He has been on the faculty of University of Pennsylvania School of Medicine and Northwestern University School of Medicine. He is a mentor at Chicago Innovation Mentors, an organization that supports Chicago area university pharmaceutical/biotechnology startup ventures.