OrphoMed to Present Phase 1 Results of ORP-101 at Digestive Disease Week 2020
ORP-101 Currently in Phase 2 Study for Treatment of Irritable Bowel Syndrome with Diarrhea
February 19, 2020
SAN FRANCISCO, CA– OrphoMed, Inc., a clinical-stage biopharmaceutical company, today announced the presentation at Digestive Disease Week® (DDW) of Phase 1 data for its lead candidate ORP-101, being developed for the treatment of irritable bowel syndrome with diarrhea.
Anthony J. Lembo, M.D., Director of the GI Motility and Functional Bowel Disorders Program at Beth Israel Deaconess Medical Center and Associate Professor at Harvard Medical School, will present the results on Monday, May 4, 12:30 – 1:30 p.m. CST, at Chicago’s McCormick Place Convention Center, South Hall A, Level 3.
“ORP-101 is uniquely designed to simultaneously modulate gastrointestinal motility and attenuate abdominal pain by interacting only with peripheral mu and kappa opioid receptors without central nervous system opioid side effects and complications,” said Dr. Lembo, who is the Chair of OrphoMed’s Scientific Advisory Board. “I am excited to lead the clinical investigation of ORP-101 in IBS-D patients, and I look forward to presenting the results of the Phase 1 single and multiple ascending dose safety, tolerability, and pharmacokinetic studies during DDW 2020.”
ORP-101 is a new chemical entity designed to have partial mu agonist and full kappa antagonist effects on peripheral opioid receptors.
- FDA Fast-track for IBS-D
- Enrolling investigators and patients for Phase 2 study http://prevailibsdstudy.com/.
About OrphoMed, Inc.
OrphoMed is a clinical-stage biopharmaceutical company focused on the development of novel first-in-class dimer therapeutics. Leveraging its proprietary dimer platform technology engineered by founder Nikhilesh Singh, Ph.D., OrphoMed is advancing ORP-101 and a pipeline of additional dimer conjugates. In May 2017, OrphoMed completed a $39 million Series A financing with New Enterprise Associates, Takeda Ventures, Pappas Capital and Relativity Healthcare. For more information please visit www.orphomed.com.
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